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PRPF3 Antibody - N-terminal region : Biotin (ARP40543_P050-Biotin)

Product Specifications

Gene Name

PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)

Gene Aliases

PRP3, RP18, HPRP3, Prp3p, HPRP3P, SNRNP90

Gene ID

9129

Swiss Prot

O43395

Accession Number

NP_004689

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF3

Target

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.[supplied by OMIM].

Partner Proteins

FAM9B; TRIM39; SART3; CEP250; AURKB; UBC; TUBG1; LIN28A; MEPCE; WWOX; WBP4; TARDBP; MMS19; FRA10AC1; SNIP1; NKAP; CTNNBL1; ZCCHC10; U2AF2; SF3B2; SLU7; SMNDC1; RBM39; PRPF3; PCBP1; MFAP1; PATL1; RBM25; NOP58; LSM1; PABPC1; PRPF6; NNT; SRRM2; SUPT16H; SF3A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

75kDa

References & Citations

Rual, J.F., (2005) Nature 437 (7062), 1173-1178

Shipping Conditions

Wet Ice

Protein Length

683

NCBI Gene Symbol

PRPF3

NCBI GB Accession Number

PRPF3

Host or Source

Rabbit

Protein Name

U4/U6 small nuclear ribonucleoprotein Prp3

Nucleotide Accession Number

NM_004698

Peptide Sequence

VDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRR

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