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HRB Antibody - middle region : Biotin (ARP40520_P050-Biotin)

Product Specifications

Gene Name

ArfGAP with FG repeats 1

Gene Aliases

HRB, RAB, RIP

Gene ID

3267

Swiss Prot

P52594

Accession Number

NP_004495

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HRB

Target

HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. HRB binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs.The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. This encoded protein binds the Rev activation domain when Rev is assembled onto its RNA target and can significantly enhance Rev activity when overexpressed. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

NYAP2; POLE2; UBC; ALAD; P3H1; NIF3L1; PPME1; IPO11; SH3GLB1; LAP3; TPRKB; DBNL; HSPBP1; GPN1; ARPC1A; ZPR1; OGT; SURF2; LPP; VCAM1; ITGA4; SUCLA2; APP; EPS15; vpr; ITSN1; APC; RNF216; EPS15L1; PKIA; XPO1; AGFG1; VAMP7; CRM1; KAP104

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

AGFG1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Song, J.H., (2007) Cancer Res. 67 (14), 6946-6955

Shipping Conditions

Wet Ice

Protein Length

562

NCBI Gene Symbol

AGFG1

NCBI GB Accession Number

AGFG1

Host or Source

Rabbit

Protein Name

Arf-GAP domain and FG repeat-containing protein 1

Nucleotide Accession Number

NM_004504

Peptide Sequence

SQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFN

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