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TARBP2 Antibody - N-terminal region : Biotin (ARP40512_T100-Biotin)

Product Specifications

Gene Name

TAR (HIV-1) RNA binding protein 2

Gene Aliases

LOQS, TRBP, TRBP1, TRBP2

Gene ID

6895

Swiss Prot

Q8WY33

Accession Number

AAL55731

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TARBP2

Target

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein.

Partner Proteins

TCEANC; STRBP; ZNF346; PRKRA; TARBP2; RRP12; RRP1B; POP1; CEBPZ; RRP9; AGO3; C1orf35; DDX50; NOC3L; TSR1; DDX27; AKAP17A; TCOF1; SRPR; SRP72; SRP54; TRMT1; SDAD1; RBM28; GPATCH4; HP1BP3; AGO2; DICER1; NUDT18; AGO1; APP; TOP1; CUL3; VAV2; NEDD4L; EIF2AK2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

8kDa

References & Citations

Bannwarth, S., J. Biol. Chem. 276 (52), 48803-48813 (2001)

Shipping Conditions

Wet Ice

Protein Length

74

NCBI Gene Symbol

TARBP2

NCBI GB Accession Number

TARBP2

Host or Source

Rabbit

Protein Name

RISC-loading complex subunit TARBP2

Nucleotide Accession Number

NM_004178

Peptide Sequence

ANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCT

Subunit

TARBP2

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