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EIF2S1 Antibody - N-terminal region : Biotin (ARP40507_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Gene Aliases

EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha

Gene ID

1965

Swiss Prot

P05198

Accession Number

NP_004085

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S1

Target

The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is

Partner Proteins

HUWE1; UBC; SUMO2; SUMO3; RPA3; RPA2; RPA1; RNF2; EIF2S3; DARS; RPS27L; EEF1E1; AIMP1; EIF2S2; RPLP0; RPL27A; RPL15; RPL13; RPL7A; QARS; MARS; MAP4; TERT; NPM1; MMS19; Dlg4; VCAM1; UPF1; ITGA4; FN1; CSNK2A1; EIF2AK2; NCOA5; POP1; STRN; YBX1; DDX1; TMED9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Puri, P., (2008) Gastroenterology 134 (2), 568-576

Shipping Conditions

Wet Ice

Protein Length

315

NCBI Gene Symbol

EIF2S1

NCBI GB Accession Number

EIF2S1

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 2 subunit 1

Nucleotide Accession Number

NM_004094

Peptide Sequence

VVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE

Subunit

1

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