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EIF2S2 Antibody - N-terminal region : Biotin (ARP40502_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Gene Aliases

EIF2, EIF2B, PPP1R67, EIF2beta, eIF-2-beta

Gene ID

8894

Swiss Prot

P20042

Accession Number

NP_003899

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S2

Target

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; SUMO2; SUMO3; RPA3; RPA2; RPA1; RNF2; SUZ12; rev; GCN1L1; EIF2S1; HMGA1; MMS19; UPF1; CSNK2B; CSNK2A1; PAXIP1; APP; CAND1; HDGF; DCC; H2AFX; KIAA1377; CCDC90B; ZBTB16; PLEKHM1; EIF2B4; EIF2B1; EIF2B3; EIF4G2; UNC119; EIF2B5; CRMP1; EIF5; PRKDC; NCK1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

333

NCBI Gene Symbol

EIF2S2

NCBI GB Accession Number

EIF2S2

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 2 subunit 2

Nucleotide Accession Number

NM_003908

Peptide Sequence

TQTEETQPSETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKK

Subunit

2

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