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PRKRA Antibody - N-terminal region : FITC (ARP40476_P050-FITC)

Selected Variant

ARP40476_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Protein kinase, interferon-inducible double stranded RNA dependent activator

Gene Aliases

RAX, PACT, DYT16, HSD14

Gene ID

8575

Swiss Prot

O75569

Accession Number

NP_003681

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRA

Target

PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA) .

Partner Proteins

ZMAT3; PRKRA; TARBP2; LYAR; STAU1; UBC; H1F0; EIF2AK2; CCDC124; C1orf35; DDX50; NOC3L; NOP16; STAU2; ZNF346; GTPBP4; DICER1; RBM34; EBNA1BP2; IFRD2; TCOF1; BMI1; SRPK3; POLR2G; MDC1; CAND1; UBE2I; SIRT7; ZFP28; KIAA1377; NKRF; SNX5; RABEPK; CEBPZ; SHC1; Z

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Kok, K.H., (2007) J. Biol. Chem. 282 (24), 17649-17657

Shipping Conditions

Wet Ice

Protein Length

313

NCBI Gene Symbol

PRKRA

NCBI GB Accession Number

PRKRA

Host or Source

Rabbit

Protein Name

Interferon-inducible double stranded RNA-dependent protein kinase activator A

Nucleotide Accession Number

NM_003690

Peptide Sequence

MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIP

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