PRKRA Antibody - N-terminal region : Biotin (ARP40476_P050-Biotin)
Product Specifications
Gene Name
Protein kinase, interferon-inducible double stranded RNA dependent activator
Gene Aliases
RAX, PACT, DYT16, HSD14
Gene ID
8575
Swiss Prot
O75569
Accession Number
NP_003681
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRA
Target
PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA) .
Partner Proteins
ZMAT3; PRKRA; TARBP2; LYAR; STAU1; UBC; H1F0; EIF2AK2; CCDC124; C1orf35; DDX50; NOC3L; NOP16; STAU2; ZNF346; GTPBP4; DICER1; RBM34; EBNA1BP2; IFRD2; TCOF1; BMI1; SRPK3; POLR2G; MDC1; CAND1; UBE2I; SIRT7; ZFP28; KIAA1377; NKRF; SNX5; RABEPK; CEBPZ; SHC1; Z
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 79%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
References & Citations
Kok, K.H., (2007) J. Biol. Chem. 282 (24), 17649-17657
Shipping Conditions
Wet Ice
Protein Length
313
NCBI Gene Symbol
PRKRA
NCBI GB Accession Number
PRKRA
Host or Source
Rabbit
Protein Name
Interferon-inducible double stranded RNA-dependent protein kinase activator A
Nucleotide Accession Number
NM_003690
Peptide Sequence
MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIP
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