XPO1 Antibody - C-terminal region: Biotin (ARP40465_P050-Biotin)
Product Specifications
Gene Name
Exportin 1 (CRM1 homolog, yeast)
Gene Aliases
Emb, CRM1, exp1, CRM-1
Gene ID
7514
Swiss Prot
O14980
Accession Number
NP_003391
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human XPO1
Target
XPO1 mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
ABL1; UBC; HUWE1; ELAVL1; KEAP1; SUMO2; SUMO3; USP16; STAU1; CDC37L1; RNF2; rev; TUBB; SCPEP1; CAMK1D; DCPS; HSPA1L; HNRNPK; GNAI3; EEF2; CAPN2; TWF2; FERMT2; UBA3; NAE1; STK24; YWHAH; YWHAE; VCL; TUFM; PCYT2; PPP5C; PPP1CA; EGFR; LOC366310; CLN5; CLN3; S
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
XPO1 is supported by BioGPS gene expression data to be expressed in HeLa, HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
123kDa
Shipping Conditions
Wet Ice
Protein Length
1071
NCBI Gene Symbol
XPO1
Protein Name
Exportin-1
Nucleotide Accession Number
NM_003400
Curated Selection
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