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SRP14 Antibody - N-terminal region : Biotin (ARP40454_T100-Biotin)

Product Specifications

Gene Name

Signal recognition particle 14kDa (homologous Alu RNA binding protein)

Gene Aliases

ALURBP

Gene ID

6727

Swiss Prot

P37108

Accession Number

NP_003125

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SRP14

Target

SRP14 belongs to the SRP14 family. The signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

Partner Proteins

HUWE1; ITGB1BP2; UBC; MDM2; LIN28A; ASB3; EED; BMI1; PKM; CBS; P3H1; IPO9; NPLOC4; DPP8; LARS; SZRD1; WDR4; PDLIM5; PLIN3; SAE1; UBA2; EIF4A3; ANP32A; SRP9; IGSF8; EEF2K; ICAM1; PAN2; IL7R; FN1; METTL18; SRP54; PRPF19; SRRM2; ACIN1; RPL14; SNRPD1; SNRPA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

SRP14 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

References & Citations

Weichenrieder, O., (2000) Nature 408 (6809), 167-173

Shipping Conditions

Wet Ice

Protein Length

136

NCBI Gene Symbol

SRP14

NCBI GB Accession Number

SRP14

Host or Source

Rabbit

Protein Name

Signal recognition particle 14 kDa protein

Nucleotide Accession Number

NM_003134

Peptide Sequence

KPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLL

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