SNRPB Antibody - middle region : Biotin (ARP40443_P050-Biotin)

Product Specifications

Gene Name

Small nuclear ribonucleoprotein polypeptides B and B1

Gene Aliases

COD, CCMS, SNRPB1, SmB/B', Sm-B/B', snRNP-B, SmB/SmB'

Gene ID

6628

Swiss Prot

Q66K91

Accession Number

NP_003082

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SNRPB

Target

SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Partner Proteins

RFX6; KRT40; L3MBTL3; GOLGA2; DAB1; TRIM23; CEP55; BANP; SS18L1; TFIP11; RBPMS; CD2BP2; CALCOCO2; HUWE1; PNMA1; PSMA3; UBC; LIN28A; MEPCE; RPA3; RPA2; RPA1; SF3A3; NCS1; CDKN2A; SRPK3; PRPF4B; SRPK2; SKIV2L; ICAM1; CD81; IGSF8; PAN2; Snrpc; LSM8; SNRPD3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

SNRPB is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.