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RPN1 Antibody - middle region : Biotin (ARP40437_P050-Biotin)

Product Specifications

Gene Name

Ribophorin I

Gene Aliases

OST1, RBPH1

Gene ID

6184

Swiss Prot

P04843

Accession Number

NP_002941

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RPN1

Target

This protein is a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBQLN1; UBC; SGTA; SUMO3; STAU1; LGR4; SUMO1; NEDD8; MDM2; ASB5; ASB11; BMI1; EED; RNF2; EGFR; ADRB2; CLN5; CLN3; AMFR; OST4; MMS19; env; UBL4A; WHSC1; VCAM1; FN1; ATF2; VCP; ESR1; ECT2; STT3B; SND1; SYNCRIP; TECR; VDAC2; SSR3; RPN2; RPSA; ILF3; SLC25A5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

607

NCBI Gene Symbol

RPN1

NCBI GB Accession Number

RPN1

Host or Source

Rabbit

Protein Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

Nucleotide Accession Number

NM_002950

Peptide Sequence

AAEARMKVACITEQVLTLVNKRIGLYRHFDETVNRYKQSRDISTLNSGKK

Subunit

1

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