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SRGN Antibody - middle region : Biotin (ARP40416_P050-Biotin)

Product Specifications

Gene Name

Serglycin

Gene Aliases

PPG, PRG, PRG1

Gene ID

5552

Swiss Prot

P10124

Accession Number

NP_002718

Host

Rabbit

Reactivity

Human, Rat, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SRGN

Target

SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBQLN1; SGTA; UBQLN4; PSRC1; CEP70; UBR4; BAG6; CCL3; PF4; GZMB; CD44; ALB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Guinea Pig: 78%; Horse: 100%; Human: 100%; Pig: 91%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

18kDa

References & Citations

Ma, D., (2008) Pediatr Blood Cancer 50 (5), 1067-1069

Shipping Conditions

Wet Ice

Protein Length

158

NCBI Gene Symbol

SRGN

NCBI GB Accession Number

SRGN

Host or Source

Rabbit

Protein Name

Serglycin

Nucleotide Accession Number

NM_002727

Peptide Sequence

RTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDY

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