PABPC1 Antibody - middle region : Biotin (ARP40403_P050-Biotin)

Product Specifications

Gene Name

Poly (A) binding protein, cytoplasmic 1

Gene Aliases

PAB1, PABP, PABP1, PABPC2, PABPL1

Gene ID

26986

Swiss Prot

P11940

Accession Number

NP_002559

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PABPC1

Target

The poly (A) -binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680) . In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly (A) -binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680) . In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

WWP2; PAIP1; TP53; UBC; SUMO2; HAUS1; CEP250; STAU1; MDM2; WWOX; RPA3; RPA2; RPA1; rev; DHX15; UBA1; SGTA; PSMD9; PIN1; P4HB; APEX1; APBB1; TMOD3; WBP4; GNPDA1; ITCH; TARDBP; SRPK2; SRPK1; CLK3; CLK2; PAIP2; CSF2; BRCA1; BAG3; TERT; GSPT2; IGSF8; RBM8A; R

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.