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NOVA1 Antibody - C-terminal region : HRP (ARP40397_P050-HRP)

Product Specifications

Gene Name

Neuro-oncological ventral antigen 1

Gene Aliases

Nova-1

Gene ID

4857

Swiss Prot

A8K603

Accession Number

NP_002506

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NOVA1

Target

NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer.This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

Partner Proteins

SRPK1; APP; PCBP1; RPP14; NOVA1; SMARCC2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Ratti, A., (2008) J. Biol. Chem. 283 (12), 7531-7541

Shipping Conditions

Wet Ice

Protein Length

507

NCBI Gene Symbol

NOVA1

NCBI GB Accession Number

NOVA1

Host or Source

Rabbit

Protein Name

CDNA FLJ75870, highly similar to Homo sapiens neuro-oncological ventral antigen 1 (NOVA1), transcript variant 1, mRNA EMBL BAF84157.1

Nucleotide Accession Number

NM_002515

Peptide Sequence

SKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG

Frequently Asked Questions

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