NCBP1 Antibody - N-terminal region : Biotin (ARP40396_P050-Biotin)
Selected Variant
ARP40396_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Nuclear cap binding protein subunit 1, 80kDa
Gene Aliases
NCBP, Sto1, CBP80
Gene ID
4686
Swiss Prot
Q09161
Accession Number
NP_002477
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1
Target
NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
POLDIP3; HUWE1; EIF4G1; UPF3B; EIF3B; MTOR; RPS6KB1; ALYREF; DDX39B; THOC3; THOC2; IVNS1ABP; UBC; LIN28B; LIN28A; ZNF346; SUMO1; SUZ12; EED; RNF2; BMI1; VAT1; MVP; TTC1; PPM1G; SERPINE2; NCL; NAP1L4; GFPT1; GARS; PUS1; TARDBP; YWHAE; RUVBL1; MPG; FN1; C17
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 88%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
92kDa
References & Citations
Narita, T., (2007) Mol. Cell 26 (3), 349-365
Shipping Conditions
Wet Ice
Protein Length
790
NCBI Gene Symbol
NCBP1
NCBI GB Accession Number
NCBP1
Host or Source
Rabbit
Protein Name
Nuclear cap-binding protein subunit 1
Nucleotide Accession Number
NM_002486
Peptide Sequence
SRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLE
Subunit
1
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