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EIF4A2 Antibody - N-terminal region : Biotin (ARP40376_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4A2

Gene Aliases

DDX2B, EIF4A, EIF4F, BM-010, eIF4A-II, eIF-4A-II

Gene ID

1974

Swiss Prot

Q14240

Accession Number

NP_001958

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4A2

Target

EIF4A2 contains 1 helicase C-terminal domain and 1 helicase ATP-binding domain. It belongs to the DEAD box helicase family. eIF4A subfamily. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5' untranslated region of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Partner Proteins

SLC16A9; PIH1D2; SSX2IP; TRIM39; TRIM36; DPPA4; IPO11; PDCD4; MDFI; EIF4A2; SUMO2; SUMO3; UBC; BAG3; CD81; VCP; ECT2; BRCA1; EIF4G3; DDX39B; EIF4A1; SUMO1; TK1; PFDN1; NEK2; Eif3a; CD4; RPAP2; EIF3F; EIF4G2; EIF4G1; CLNS1A; RPS29; CMBL; VAC14; EIF3L; EIF3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Sarkar, M., (2005) FEBS Lett. 579 (16), 3449-3460

Shipping Conditions

Wet Ice

Protein Length

407

NCBI Gene Symbol

EIF4A2

NCBI GB Accession Number

EIF4A2

Host or Source

Rabbit

Protein Name

Eukaryotic initiation factor 4A-II

Nucleotide Accession Number

NM_001967

Peptide Sequence

MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYA

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