EIF4B Antibody - middle region : Biotin (ARP40360_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4B

Gene Aliases

EIF-4B, PRO1843

Gene ID

1975

Swiss Prot

P23588

Accession Number

NP_001408

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human EIF4B

Target

IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Partner Proteins

UBC; ASB2; ZBTB1; SAMHD1; XPO7; SEC23A; PRMT3; CUL4B; USP11; SF1; XRCC5; OSBP; NARS; Stk11; CTNNA1; PARK2; FBXO6; PAN2; CSNK2A1; EIF4A3; YWHAE; MAGOH; SMURF1; NUP107; PHAX; SLC4A1AP; CCT6B; NUP153; POLR1C; RPL29; MYH9; EIF4G2; EIF4G1; EIF4A1; CSTF2; CUL3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

EIF4B is strongly supported by BioGPS gene expression data to be expressed in ACHN

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.