EIF4B Antibody - C-terminal region : FITC (ARP40359_T100-FITC)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4B

Gene Aliases

EIF-4B, PRO1843

Gene ID

1975

Swiss Prot

P23588

Accession Number

NP_001408

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B

Target

IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Partner Proteins

UBC; ASB2; ZBTB1; SAMHD1; XPO7; SEC23A; PRMT3; CUL4B; USP11; SF1; XRCC5; OSBP; NARS; Stk11; CTNNA1; PARK2; FBXO6; PAN2; CSNK2A1; EIF4A3; YWHAE; MAGOH; SMURF1; NUP107; PHAX; SLC4A1AP; CCT6B; NUP153; POLR1C; RPL29; MYH9; EIF4G2; EIF4G1; EIF4A1; CSTF2; CUL3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

EIF4B is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 79%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.