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CSTF3 Antibody - middle region : FITC (ARP40353_P050-FITC)

Product Specifications

Gene Name

Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa

Gene Aliases

CSTF-77

Gene ID

1479

Swiss Prot

Q12996

Accession Number

NP_001317

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CSTF3

Target

CSTF3 is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF) . This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF) . This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

RBBP6; UBC; WWOX; rev; HECW2; POLR2A; WHSC1; CSTF1; CSTF2T; GAPDH; CSTF2; CUL3; HNRNPA1; CPSF1; RRAGA; CDC73; VHL; E2F4; ASF1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CSTF3 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

83kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

717

NCBI Gene Symbol

CSTF3

NCBI GB Accession Number

CSTF3

Host or Source

Rabbit

Protein Name

Cleavage stimulation factor subunit 3

Nucleotide Accession Number

NM_001326

Peptide Sequence

FEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKSK

Subunit

3

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