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CSTF2 Antibody - N-terminal region : Biotin (ARP40351_P050-Biotin)

Product Specifications

Gene Name

Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa

Gene Aliases

CstF-64

Gene ID

1478

Swiss Prot

P33240

Accession Number

NP_001316

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CSTF2

Target

CSTF2 is a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBQLN1; SPAG8; SS18L1; TFG; HGS; RBBP6; ZNF341; UBC; WWOX; rev; LSM8; GET4; BABAM1; AKAP2; MAP4; CDKN2A; PARN; BARD1; CPSF2; CPSF3; CPSF6; NUP153; MAX; EIF4B; DDX1; DDB1; CSTF3; APP; UBQLN4; POLR2A; CDC73; SRRM1; UL48; KIAA1377; EEF1G; FEZ1; SYMPK; CHD3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

CSTF2 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 85%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

577

NCBI Gene Symbol

CSTF2

NCBI GB Accession Number

CSTF2

Host or Source

Rabbit

Protein Name

Cleavage stimulation factor subunit 2

Nucleotide Accession Number

NM_001325

Peptide Sequence

VDPEIALKILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSMNQQNPQAPQA

Subunit

2

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