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CDC5L Antibody - middle region : Biotin (ARP40347_P050-Biotin)

Product Specifications

Gene Name

CDC5 cell division cycle 5-like (S. pombe)

Gene Aliases

CDC5, CEF1, PCDC5RP, CDC5-LIKE, dJ319D22.1

Gene ID

988

Swiss Prot

Q99459

Accession Number

NP_001244

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CDC5L

Target

CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. CDC5L has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

GOLGA2; FUS; GOLGA8F; GOLGA8EP; STAU1; UBC; LIN28A; RPA3; RPA2; RPA1; ERG; WWOX; TCP1; EED; rev; TARDBP; CSNK2A2; EMID1; CDT1; MCM10; BCAS2; GRB14; CDKN2A; CDKN1A; WHSC1; SMARCD1; ORC5; ORC2; ORC1; MCM5; MCM4; MCM3; LMO2; KRT18; EIF4A3; MAGOH; PAXIP1; MDC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

CDC5L is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Jarjanazi, H., (2008) Hum. Mutat. 29 (4), 461-467

Shipping Conditions

Wet Ice

Protein Length

802

NCBI Gene Symbol

CDC5L

NCBI GB Accession Number

CDC5L

Host or Source

Rabbit

Protein Name

Cell division cycle 5-like protein

Nucleotide Accession Number

NM_001253

Peptide Sequence

LHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDE

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