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ADARB1 Antibody - N-terminal region : HRP (ARP40343_P050-HRP)

Product Specifications

Gene Name

Adenosine deaminase, RNA-specific, B1

Gene Aliases

RED1, ADAR2, DRABA2, DRADA2, NEDHYMS

Gene ID

104

Swiss Prot

P78563

Accession Number

NP_001028221

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1

Target

ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Partner Proteins

EBNA1BP2; IFRD2; CCDC124; NIFK; C7orf50; C1orf35; STRBP; BRIX1; SDAD1; ZFR; NOP16; MRTO4; RRS1; BMI1; APP; UBC; PPP2CB; WWP2; PIN1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

80kDa

References & Citations

Cenci, C., (2008) J. Biol. Chem. 283 (11), 7251-7260

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ADARB1 (ARP40343_P050-HRP) antibody

Protein Length

729

NCBI Gene Symbol

ADARB1

NCBI GB Accession Number

ADARB1

Host or Source

Rabbit

Protein Name

Double-stranded RNA-specific editase 1

Nucleotide Accession Number

NM_001033049

Peptide Sequence

NMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEE

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