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RBM9 Antibody - N-terminal region : Biotin (ARP40339_P050-Biotin)

Selected Variant

ARP40339_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

RNA binding protein, fox-1 homolog (C. elegans) 2

Gene Aliases

RTA, fxh, FOX2, RBM9, Fox-2, HNRBP2, HRNBP2, dJ106I20.3

Gene ID

23543

Swiss Prot

O43251

Accession Number

NP_001026865

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RBM9

Target

RBM9 is a RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MAPK1IP1L; NAF1; C1orf94; BOLL; VAC14; DAZAP2; MAGED1; RNF8; ATXN1; PSMA3; HNRNPF; DAB1; CAMK2B; RPA3; RPA2; RPA1; BMI1; ELAVL1; DDX5; RBM42; RBM22; RBM23; APH1A; RBFOX2; U2AF2; KHDRBS1; SF3A1; PSMF1; QKI; SNRPC; SMN1; PTBP1; HNRNPK; HNRNPH2; VCP; ATXN1L

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Yang, G., (2008) Blood 111 (1), 392-401

Shipping Conditions

Wet Ice

Protein Length

380

NCBI Gene Symbol

RBFOX2

NCBI GB Accession Number

RBFOX2

Host or Source

Rabbit

Protein Name

RNA binding protein fox-1 homolog 2

Nucleotide Accession Number

NM_001031695

Peptide Sequence

STQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRL

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