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U2AF1L4 Antibody - N-terminal region : FITC (ARP40325_P050-FITC)

Selected Variant

ARP40325_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

U2 small nuclear RNA auxiliary factor 1

Gene Aliases

U2af26, U2AF1L3, U2AF1RS3, U2AF1-RS3, U2AF1L3V1

Gene ID

199746

Swiss Prot

Q8WU68

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4

Target

U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.

Partner Proteins

MDM2; SUZ12; UBC; ELAVL1; GIGYF2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

24kDa

Shipping Conditions

Wet Ice

Protein Length

220

NCBI Gene Symbol

U2AF1L4

NCBI GB Accession Number

U2AF1L4

Host or Source

Rabbit

Protein Name

Splicing factor U2AF 26 kDa subunit

Peptide Sequence

KIGVCRHGDRCSRLHNKPTFSQTIVLLNLYRNPQNTAQTADGSHCHVSDV

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