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FUS Antibody - N-terminal region : FITC (ARP40278_P050-FITC)

Product Specifications

Gene Name

Fused in sarcoma

Gene Aliases

TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2

Gene ID

2521

Swiss Prot

P35637

Accession Number

NP_001010850

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FUS

Target

FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.

Partner Proteins

TBPL1; TRIP4; RPL14; HIST2H2BE; RAB7A; TUBA1A; DDX42; ATXN2L; CPSF6; NUDT21; YWHAQ; CKAP4; SF3A3; CCT8; PAICS; CCT2; CCT4; CCT7; SYNCRIP; TUBA1B; SF3A1; SF3B4; ABCF2; SAE1; SF1; YWHAZ; VCP; UBA1; UBC; TUFM; CCT3; HSP90B1; TP73; TKT; TCP1; TCEB1; STATH; ST

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

FUS is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53 kDa

References & Citations

Sato, S., (2005) Gastroenterology 129 (4), 1225-1236

Shipping Conditions

Wet Ice

Product Datasheet

Anti-FUS (ARP40278_P050-FITC) antibody

Protein Length

526

NCBI Gene Symbol

FUS

NCBI GB Accession Number

FUS

Host or Source

Rabbit

Nucleotide Accession Number

NM_001010850

Peptide Sequence

MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY

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