FUS Antibody - N-terminal region : Biotin (ARP40278_P050-Biotin)
Selected Variant
ARP40278_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Fused in sarcoma
Gene Aliases
TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2
Gene ID
2521
Swiss Prot
P35637
Accession Number
NP_001010850
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human FUS
Target
FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.
Partner Proteins
TBPL1; TRIP4; RPL14; HIST2H2BE; RAB7A; TUBA1A; DDX42; ATXN2L; CPSF6; NUDT21; YWHAQ; CKAP4; SF3A3; CCT8; PAICS; CCT2; CCT4; CCT7; SYNCRIP; TUBA1B; SF3A1; SF3B4; ABCF2; SAE1; SF1; YWHAZ; VCP; UBA1; UBC; TUFM; CCT3; HSP90B1; TP73; TKT; TCP1; TCEB1; STATH; ST
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
FUS is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53 kDa
References & Citations
Sato, S., (2005) Gastroenterology 129 (4), 1225-1236
Shipping Conditions
Wet Ice
Protein Length
526
NCBI Gene Symbol
FUS
NCBI GB Accession Number
FUS
Host or Source
Rabbit
Nucleotide Accession Number
NM_001010850
Peptide Sequence
MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY
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