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EXOSC10 Antibody C-terminal region : Biotin (ARP40227_P050-Biotin)

Product Specifications

Gene Name

Exosome component 10

Gene Aliases

P2, p3, p4, RRP6, PMSCL, Rrp6p, PM-Scl, PMSCL2, PM/Scl-100

Gene ID

5394

Swiss Prot

Q01780

Accession Number

NP_001001998

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10

Target

EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.

Partner Proteins

SUMO2; UBC; SUMO1; RPA3; RPA2; RPA1; NOMO2; EXOSC6; FERMT3; CHPF; LSM2; EXOSC5; FOXRED1; EXOSC4; XRN1; LSM8; B9D1; USP21; UPF2; NOMO1; EXOSC7; DIS3; EXOSC8; IMMT; RUVBL2; EIF3M; TOX4; SSRP1; SKIV2L; LCAT; DXO; ALDH1B1; AICDA; ESR1; EXOSC3; EXOSC9; DIS3L

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

EXOSC10 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

101kDa

References & Citations

Van (2007) RNA 13 (7), 1027-1035

Shipping Conditions

Wet Ice

Protein Length

885

NCBI Gene Symbol

EXOSC10

NCBI GB Accession Number

EXOSC10

Host or Source

Rabbit

Protein Name

Exosome component 10

Nucleotide Accession Number

NM_001001998

Peptide Sequence

ACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP

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