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EXOSC10 Antibody - C-terminal region : FITC (ARP40225_T100-FITC)

Product Specifications

Gene Name

Exosome component 10

Gene Aliases

P2, p3, p4, RRP6, PMSCL, Rrp6p, PM-Scl, PMSCL2, PM/Scl-100

Gene ID

5394

Swiss Prot

Q01780

Accession Number

NP_001001998

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EXOSC10

Target

EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.

Partner Proteins

SUMO2; UBC; SUMO1; RPA3; RPA2; RPA1; NOMO2; EXOSC6; FERMT3; CHPF; LSM2; EXOSC5; FOXRED1; EXOSC4; XRN1; LSM8; B9D1; USP21; UPF2; NOMO1; EXOSC7; DIS3; EXOSC8; IMMT; RUVBL2; EIF3M; TOX4; SSRP1; SKIV2L; LCAT; DXO; ALDH1B1; AICDA; ESR1; EXOSC3; EXOSC9; DIS3L

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

EXOSC10 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

References & Citations

Lehner, B. (2004) Genome Res. 14 (7), 1315-1323

Shipping Conditions

Wet Ice

Protein Length

885

NCBI Gene Symbol

EXOSC10

NCBI GB Accession Number

EXOSC10

Host or Source

Rabbit

Protein Name

Exosome component 10

Nucleotide Accession Number

NM_001001998

Peptide Sequence

FAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG

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