KRT18 Antibody - C-terminal region : Biotin (ARP40206_T100-Biotin)

Product Specifications

Gene Name

Keratin 18

Gene Aliases

K18, CK-18, CYK18

Gene ID

3875

Swiss Prot

P05783

Accession Number

NP_000215

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KRT18

Target

KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Partner Proteins

KRT18; GOLGA2; UBC; HAUS1; CCDC146; MDM2; EED; HNRNPU; FLII; FKBP3; DDX1; C14orf166; RTCB; CNOT1; SEC16A; RPL14; RFC2; UPF2; BBS7; PAN2; BBS4; BBS2; BBS1; SMARCD1; ORC5; NOS2; KRT8; KPNA2; ITGA4; HRAS; GRN; FN1; EP300; ATF2; CDH1; CDC5L; YTHDC1; PIAS4; TX

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

KRT18 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 77%; Rat: 100%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.