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INSIG1 Antibody - middle region : Biotin (ARP40159_P050-Biotin)

Product Specifications

Gene Name

Insulin induced gene 1

Gene Aliases

CL6

Gene ID

3638

Swiss Prot

A4D2M9

Accession Number

NP_938150

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human INSIG1

Target

Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR) - and sterol regulatory element-binding protein (SREBP) -mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane prote

Partner Proteins

UBC; HMGCR; FAF2; SCAP; ERLIN2; ERLIN1; VCP; AMFR; PGRMC1; POR; SREBF1; ELAVL1; RNF139; INSIG2; PSMC3; PSMA7; INSIG1; VAPA; VAPB; SREBF2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Roth, A., (2008) Mol. Pharmacol. 73 (4), 1282-1289

Shipping Conditions

Wet Ice

Protein Length

330

NCBI Gene Symbol

INSIG1

NCBI GB Accession Number

INSIG1

Host or Source

Rabbit

Protein Name

Insulin induced gene 1 EMBL EAL23728.1

Nucleotide Accession Number

NM_198336

Peptide Sequence

ITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGR

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