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Taf1c Antibody - C-terminal region : HRP (ARP40130_P050-HRP)

Selected Variant

ARP40130_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

TATA box binding protein (Tbp) -associated factor, RNA polymerase I, C

Gene Aliases

MTAFI, Tafi95, mTAFI95

Gene ID

21341

Swiss Prot

Q6PDZ2

Accession Number

NP_067416

Host

Rabbit

Reactivity

Mouse, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Partner Proteins

Tbp; Taf1b; Taf1a

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Guinea Pig: 85%; Mouse: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

Shipping Conditions

Wet Ice

Protein Length

836

NCBI Gene Symbol

TAF1C

NCBI GB Accession Number

Taf1c

Host or Source

Rabbit

Protein Name

TATA box-binding protein-associated factor RNA polymerase I subunit C

Nucleotide Accession Number

NM_021441

Peptide Sequence

RRHRGETSETQTQSKRPKRRTQLSSTFSSFTSYLDSPDASSAPRSQDLST

Subunit

C

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