Ppargc1a Antibody - middle region : Biotin (ARP40129_P050-Biotin)

Product Specifications

Gene Name

Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

Gene Aliases

Pgc, Pgc1, PGC-1, Pgco1, Gm11133, Ppargc1, Pgc-1alpha, A830037N07Rik, PPARGC-1-alpha

Gene ID

19017

Swiss Prot

O70343

Accession Number

NP_032930

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse Ppargc1a

Target

Ppargc1a is a transcriptional coactivator for steroid receptors and nuclear receptors. Ppargc1a greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Ppargc1a can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.

Partner Proteins

Yy1; Akt1; Pparg; Cdk7; Mybbp1a; Sirt1; Hnf4a; Nr5a1; Lhb; NR1I2; Esrra; Nr1h3; Ncoa1; Foxo1; Pck1; G6pc

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 83%; Goat: 86%; Guinea Pig: 92%; Horse: 92%; Human: 83%; Mouse: 100%; Rabbit: 92%; Rat: 92%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.