SALL3 Antibody : HRP (ARP39971_P050-HRP)
Selected Variant
ARP39971_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Sal-like 3 (Drosophila)
Gene Aliases
ZNF796
Gene ID
27164
Swiss Prot
Q9BXA9
Accession Number
NP_741996
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence RRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSV
Target
This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Partner Proteins
DNMT3A; CHD7; UBC; SOX2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 79%; Human: 100%; Mouse: 100%; Pig: 85%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
135 kDa
Shipping Conditions
Wet Ice
Protein Length
1300
NCBI Gene Symbol
SALL3
NCBI GB Accession Number
SALL3
Host or Source
Rabbit
Protein Name
Sal-like protein 3
Nucleotide Accession Number
NM_171999
Peptide Sequence
RRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSV
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