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SPIC Antibody - middle region : Biotin (ARP39882_P050-Biotin)

Product Specifications

Gene Name

Spi-C transcription factor (Spi-1/PU.1 related)

Gene Aliases

SPI-C

Gene ID

121599

Swiss Prot

Q8N5J4

Accession Number

NP_689536

Host

Rabbit

Reactivity

Human, Cow, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SPIC

Target

SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. SPIC is a transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC regulates VCAM1 gene expression.

Partner Proteins

APP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Horse: 79%; Human: 100%; Pig: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

References & Citations

Carlsson, R., (2006) Biochem. Biophys. Res. Commun. 344 (4), 1155-1160

Shipping Conditions

Wet Ice

Protein Length

248

NCBI Gene Symbol

SPIC

NCBI GB Accession Number

SPIC

Host or Source

Rabbit

Protein Name

Transcription factor Spi-C

Nucleotide Accession Number

NM_152323

Peptide Sequence

LQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHD

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