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MSL3L1 Antibody - N-terminal region : FITC (ARP39783_P050-FITC)

Product Specifications

Gene Name

Male-specific lethal 3 homolog (Drosophila)

Gene Aliases

MRSXBA, MRXS36, MRXSBA, MSL3L1

Gene ID

10943

Swiss Prot

Q8N5Y2

Accession Number

NP_523353

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MSL3L1

Target

MSL3L1 is a nuclear protein, which is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

Partner Proteins

PAF1; DYRK1B; SOX2; UBC; CDK6; APP; HIST4H4; HIST3H3; MSL1; KAT8; PRKDC; MSL2; HIST1H4A; HIST1H3A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MSL3 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Smith, E.R., (2005) Mol. Cell. Biol. 25 (21), 9175-9188

Shipping Conditions

Wet Ice

Protein Length

521

NCBI Gene Symbol

MSL3

NCBI GB Accession Number

MSL3

Host or Source

Rabbit

Protein Name

Male-specific lethal 3 homolog

Nucleotide Accession Number

NM_078629

Peptide Sequence

MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIP

Frequently Asked Questions

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