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PML Antibody - middle region : FITC (ARP39753_P050-FITC)

Product Specifications

Gene Name

Promyelocytic leukemia

Gene Aliases

MYL, RNF71, PP8675, TRIM19

Gene ID

5371

Swiss Prot

P29590

Accession Number

NP_150241

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PML

Target

PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor an

Partner Proteins

RPL11; RPL5; SUMO1; UBC; TP53; SUMO2; SUMO3; MDM2; RNF4; EGFR; NCOA2; SP100; DAXX; MAPK7; HDAC1; ATXN1; ATRX; ASF1A; EHMT2; HIRA; HTT; H3F3A; ATF7IP; PML; JAK1; EIF4E; GLIS2; UBE2I; smt3; HDAC11; HDAC6; LMNA; RNF111; CDK6; CDK2; CDK1; CASP8AP2; RBX1; SH3G

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that PML is expressed in ACHN

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

References & Citations

Eun, B., (2008) J. Biol. Chem. 283 (9), 5939-5949

Shipping Conditions

Wet Ice

Specificity

Isoform 1, 9, 10 and 11 specific

Protein Length

882

NCBI Gene Symbol

PML

NCBI GB Accession Number

PML

Host or Source

Rabbit

Protein Name

Protein PML

Nucleotide Accession Number

NM_033238

Peptide Sequence

TTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQ

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