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L3MBTL2 Antibody - C-terminal region : HRP (ARP39670_T100-HRP)

Selected Variant

ARP39670_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

L (3) mbt-like 2 (Drosophila)

Gene Aliases

L3MBT, H-l (3) mbt-l

Gene ID

83746

Swiss Prot

Q969R5

Accession Number

NP_113676

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2

Target

L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

Partner Proteins

TRIM42; STAC3; PHF10; TBC1D9B; PAICS; AES; SUMO2; SUMO1; PIAS1; HIST1H4A; HIST1H3A; RNF2; MPP3; PCGF6; RYBP; YAF2; SMARCAD1; HIST4H4; CBX3; HIST3H3; E2F6; Lin54; HDAC3; MEAF6; STAM2; RB1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

79kDa

References & Citations

Collins, J.E., Genome Biol. 5 (10), R84 (2004)

Shipping Conditions

Wet Ice

Protein Length

705

NCBI Gene Symbol

L3MBTL2

NCBI GB Accession Number

L3MBTL2

Host or Source

Rabbit

Protein Name

Lethal (3) malignant brain tumor-like protein 2

Nucleotide Accession Number

NM_031488

Peptide Sequence

LLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVEN

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