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MXD3 Antibody - N-terminal region : Biotin (ARP39663_P050-Biotin)

Product Specifications

Gene Name

MAX dimerization protein 3

Gene Aliases

MYX, MAD3, BHLHC13

Gene ID

83463

Swiss Prot

Q9BW11

Accession Number

NP_112590

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Target

MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.

Partner Proteins

NOTCH2NL; KRTAP10-7; UBC; NFKB1; MAGEA11; MAX; SIN3A; SMC3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

References & Citations

Hurlin, P.J., (1995) EMBO J. 14 (22), 5646-5659

Shipping Conditions

Wet Ice

Protein Length

206

NCBI Gene Symbol

MXD3

NCBI GB Accession Number

MXD3

Host or Source

Rabbit

Protein Name

Max dimerization protein 3

Nucleotide Accession Number

NM_031300

Peptide Sequence

MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQ

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