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TRIM8 Antibody - N-terminal region : Biotin (ARP39655_P050-Biotin)

Product Specifications

Gene Name

Tripartite motif containing 8

Gene Aliases

GERP, RNF27

Gene ID

81603

Swiss Prot

Q9BZR9

Accession Number

NP_112174

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM8

Target

TRIM8 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.

Partner Proteins

BRAP; TRIM25; PCGF5; MSL2; RNF141; TRIM2; USP7; TP53; CCNH; OTUB2; USP21; USP39; USP2; TNFAIP3; UBE2D2; TRIM47; TRIM15; TRIM8; RAD18; TRIM39; RNF111; RC3H2; RNF138; RNF181; RCHY1; RNF41; TRIM43; UHRF2; TRIM9; RNF7; TRIM24; RNF113A; MKRN3; TRAF5; TRIM21; S

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Carinci, F., (2007) Transl Res 150 (4), 233-245

Shipping Conditions

Wet Ice

Protein Length

551

NCBI Gene Symbol

TRIM8

NCBI GB Accession Number

TRIM8

Host or Source

Rabbit

Protein Name

Probable E3 ubiquitin-protein ligase TRIM8

Nucleotide Accession Number

NM_030912

Peptide Sequence

RGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEK

Frequently Asked Questions

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