CBLL1 Antibody - C-terminal region: FITC (ARP39623_T100-FITC)
Product Specifications
Gene Name
Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
Gene Aliases
HAKAI, RNF188
Gene ID
79872
Swiss Prot
Q75N03
Accession Number
NP_079090
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1
Target
Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1; MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A; MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Partner Proteins
DGCR6; SUMO1; UBC; CDH1; RNF2; YWHAQ; SFPQ; Cbll1; ESR1; CTTN; DOK1; SRC; CDC42
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
Shipping Conditions
Wet Ice
Protein Length
491
NCBI Gene Symbol
CBLL1
Protein Name
E3 ubiquitin-protein ligase Hakai
Nucleotide Accession Number
NM_024814
Curated Selection
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