PHF1 Antibody - C-terminal region : Biotin (ARP39589_P050-Biotin)
Product Specifications
Gene Name
PHD finger protein 1
Gene Aliases
PCL1, PHF2, hPHF1, MTF2L2, TDRD19C
Gene ID
5252
Swiss Prot
O43189
Accession Number
NP_077084
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PHF1
Target
PHF1 has significant sequence similarity with Drosophila Polycomblike. It contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.
Partner Proteins
ATXN7L1; BIRC7; VAC14; HSD17B14; RBPMS; CALCOCO2; PDLIM7; TFCP2; NAB2; TRIM23; SUZ12; EZH2; NEK6; TP53; SUMO1; HIC1; ELAVL1; UBC; RAD50; NCR1; EED; SMC1A; XRCC5; RBBP7; XRCC6; DHX9; HIST1H3J; HIST1H3G; HIST1H3I; HIST1H3E; HIST1H3C; HIST1H3A; HIST1H3F; HIS
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
References & Citations
Hong, Z., (2008) Nucleic Acids Res. 36 (9), 2939-2947
Shipping Conditions
Wet Ice
Protein Length
567
NCBI Gene Symbol
PHF1
NCBI GB Accession Number
PHF1
Host or Source
Rabbit
Protein Name
PHD finger protein 1
Nucleotide Accession Number
NM_024165
Peptide Sequence
SAPPSPLCRSLSPGTGGGVRGGVGYLSRGDPVRVLARRVRPDGSVQYLVE
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