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BCL11A Antibody - C-terminal region : FITC (ARP39569_P050-FITC)

Selected Variant

ARP39569_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

B-cell CLL/lymphoma 11A (zinc finger protein)

Gene Aliases

EVI9, CTIP1, DILOS, ZNF856, HBFQTL5, BCL11A-L, BCL11A-S, BCL11a-M, BCL11A-XL

Gene ID

53335

Swiss Prot

Q9H165

Accession Number

NP_075044

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human BCL11A

Target

BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.

Partner Proteins

GMCL1P1; ZBTB24; NCK2; LMO1; NR2E3; NR2E1; NR2F2; NR2F1; NR2F6; HDAC2; HDAC1; CDCA3; YME1L1; CDK6; CDK4; ACTC1; APP; UBC; BCL6; BCL11A; Sumo1; SUMO2; SUMO3; SIRT1; MBD3; MTA2; MTA1; CHD4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

Shipping Conditions

Wet Ice

Protein Length

835

NCBI Gene Symbol

BCL11A

NCBI GB Accession Number

BCL11A

Host or Source

Rabbit

Protein Name

B-cell lymphoma/leukemia 11A

Nucleotide Accession Number

NM_022893

Peptide Sequence

YACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKWHSDR

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