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TUT1 Antibody - middle region : HRP (ARP39567_P050-HRP)

Selected Variant

ARP39567_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Terminal uridylyl transferase 1, U6 snRNA-specific

Gene Aliases

PAPD2, RBM21, TENT1, URLC6, TUTase, STARPAP

Gene ID

64852

Swiss Prot

A8K995

Accession Number

NP_073741

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TUT1

Target

TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]) .[supplied by OMIM].

Partner Proteins

HUWE1; IL32; SUMO2; TIMELESS; PIN1; FBXO6; SOX2; CPSF3; CPSF1; HMOX1; UBC; YWHAQ; MEPCE; USP15; SART3; PRPF4; USP4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

94kDa

References & Citations

Gonzales, M.L., (2008) J. Biol. Chem. 283 (18), 12665-12673

Shipping Conditions

Wet Ice

Protein Length

874

NCBI Gene Symbol

TUT1

NCBI GB Accession Number

TUT1

Host or Source

Rabbit

Protein Name

Speckle targeted PIP5K1A-regulated poly (A) polymerase

Nucleotide Accession Number

NM_022830

Peptide Sequence

EGAGGGAGTRAGWLATEAQVTQELKGLSGGEERPETEPLLSFVASVSPAD

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