TUT1 Antibody - middle region : FITC (ARP39567_P050-FITC)
Product Specifications
Gene Name
Terminal uridylyl transferase 1, U6 snRNA-specific
Gene Aliases
PAPD2, RBM21, TENT1, URLC6, TUTase, STARPAP
Gene ID
64852
Swiss Prot
A8K995
Accession Number
NP_073741
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TUT1
Target
TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]) .[supplied by OMIM].
Partner Proteins
HUWE1; IL32; SUMO2; TIMELESS; PIN1; FBXO6; SOX2; CPSF3; CPSF1; HMOX1; UBC; YWHAQ; MEPCE; USP15; SART3; PRPF4; USP4
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
94kDa
References & Citations
Gonzales, M.L., (2008) J. Biol. Chem. 283 (18), 12665-12673
Shipping Conditions
Wet Ice
Protein Length
874
NCBI Gene Symbol
TUT1
NCBI GB Accession Number
TUT1
Host or Source
Rabbit
Protein Name
Speckle targeted PIP5K1A-regulated poly (A) polymerase
Nucleotide Accession Number
NM_022830
Peptide Sequence
EGAGGGAGTRAGWLATEAQVTQELKGLSGGEERPETEPLLSFVASVSPAD
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