PRDM12 Antibody - C-terminal region: FITC (ARP39504_T100-FITC)
Product Specifications
Gene Name
PR domain containing 12
Gene Aliases
PFM9, HSAN8
Gene ID
59335
Swiss Prot
Q9H4Q4
Accession Number
NP_067632
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
Target
PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain; the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
367
NCBI Gene Symbol
PRDM12
Protein Name
PR domain zinc finger protein 12
Nucleotide Accession Number
NM_021619
Curated Selection
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