UTX Antibody - N-terminal region : Biotin (ARP39482_P050-Biotin)
Selected Variant
ARP39482_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Lysine (K) -specific demethylase 6A
Gene Aliases
UTX, KABUK2, bA386N14.2
Gene ID
7403
Swiss Prot
O15550
Accession Number
NP_066963
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human UTX
Target
UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Partner Proteins
KMT2D; WDR5; ASH2L; RBBP5; SMAD9; HIST2H3C; SRF; SMARCA4; GATA4; NKX2-5; TBX5; UBC; HIST1H3A; WDR82; PAXIP1; NCOA6; TLE1; PROSER1; KMT2C; N4BP2; PPP6R3; ZNF281; HIST3H3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
154kDa
Shipping Conditions
Wet Ice
Protein Length
1401
NCBI Gene Symbol
KDM6A
NCBI GB Accession Number
KDM6A
Host or Source
Rabbit
Protein Name
Lysine-specific demethylase 6A
Nucleotide Accession Number
NM_021140
Peptide Sequence
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALG
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PB9622-HRP 100 µg/Vial
Anti-ERVW-1 Antibody Picoband® (HRP Conjugate)
Sign In for Pricing
View Details 
PA1917-HRP 100 µg/Vial
Anti-Iduronate 2 sulfatase/IDS Antibody Picoband®, HRP Conjugate
Sign In for Pricing
View Details 
AZA0A8M6YZJ1-carrier-free 100 µg/Vial
Anti-Zebrafish CDT1 Antibody Picoband®
Sign In for Pricing
View Details 
BNUB2038-500 1x 500 µL
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2038), 0.2mg/mL
Sign In for Pricing
View Details