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MNT Antibody - N-terminal region : Biotin (ARP39412_P050-Biotin)

Product Specifications

Gene Name

MAX binding protein

Gene Aliases

ROX, MAD6, MXD6, bHLHd3, lncRNA-HAL

Gene ID

4335

Swiss Prot

Q99583

Accession Number

NP_064706

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MNT

Target

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

Dlg4; ELAVL1; CEBPA; MAX; MAD1L1; MYC; HDAC1; SIN3A; MNT; MLX; HMGB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MNT is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Horse: 80%; Human: 100%; Mouse: 93%; Pig: 80%; Rabbit: 93%; Rat: 93%; Yeast: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Montagne, M., (2008) J. Mol. Biol. 376 (1), 141-152

Shipping Conditions

Wet Ice

Protein Length

582

NCBI Gene Symbol

MNT

NCBI GB Accession Number

MNT

Host or Source

Rabbit

Protein Name

Max-binding protein MNT

Nucleotide Accession Number

NM_020310

Peptide Sequence

SIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAH

Frequently Asked Questions

More Discoveries

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