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ARNTL2 Antibody - N-terminal region : Biotin (ARP39398_P050-Biotin)

Product Specifications

Gene Name

Aryl hydrocarbon receptor nuclear translocator-like 2

Gene Aliases

CLIF, MOP9, BMAL2, PASD9, bHLHe6

Gene ID

56938

Swiss Prot

Q8WYA1

Accession Number

NP_064568

Host

Rabbit

Reactivity

Human, Mouse, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL2

Target

ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.

Partner Proteins

NPAS2; UBC; EPAS1; CLOCK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Mouse: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71kDa

References & Citations

Shi, J., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

636

NCBI Gene Symbol

ARNTL2

NCBI GB Accession Number

ARNTL2

Host or Source

Rabbit

Protein Name

Aryl hydrocarbon receptor nuclear translocator-like protein 2

Nucleotide Accession Number

NM_020183

Peptide Sequence

PTAMGSFSSHMTEFPRKRKGSDSDPSQSGIMTEKVVEKLSQNPLTYLLST

Frequently Asked Questions

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