POLE4 Antibody - N-terminal region : FITC (ARP39392_P050-FITC)
Product Specifications
Gene Name
Polymerase (DNA-directed), epsilon 4 (p12 subunit)
Gene Aliases
P12, YHHQ1
Gene ID
56655
Swiss Prot
Q9NR33
Accession Number
NP_063949
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human POLE4
Target
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Partner Proteins
NFYB; gag-pol; NUP133; POLE3; MAP3K7; UBC; YEATS2; POLE4; UBE3A; HSPA13; POLE2; POLE; RAD17
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
12kDa
References & Citations
Hillier, L.W., (2005) Nature 434 (7034), 724-731
Shipping Conditions
Wet Ice
Protein Length
117
NCBI Gene Symbol
POLE4
NCBI GB Accession Number
POLE4
Host or Source
Rabbit
Protein Name
DNA polymerase epsilon subunit 4
Nucleotide Accession Number
NM_019896
Peptide Sequence
MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALV
Subunit
4
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