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POLE4 Antibody - N-terminal region : Biotin (ARP39392_P050-Biotin)

Product Specifications

Gene Name

Polymerase (DNA-directed), epsilon 4 (p12 subunit)

Gene Aliases

P12, YHHQ1

Gene ID

56655

Swiss Prot

Q9NR33

Accession Number

NP_063949

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLE4

Target

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

Partner Proteins

NFYB; gag-pol; NUP133; POLE3; MAP3K7; UBC; YEATS2; POLE4; UBE3A; HSPA13; POLE2; POLE; RAD17

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

12kDa

References & Citations

Hillier, L.W., (2005) Nature 434 (7034), 724-731

Shipping Conditions

Wet Ice

Product Datasheet

Anti-POLE4 (ARP39392_P050-Biotin) antibody

Protein Length

117

NCBI Gene Symbol

POLE4

NCBI GB Accession Number

POLE4

Host or Source

Rabbit

Protein Name

DNA polymerase epsilon subunit 4

Nucleotide Accession Number

NM_019896

Peptide Sequence

MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALV

Subunit

4

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